Never tried it but you are talking about a 50% increase in muzzle velocities. What are the chamber pressures on those SMC loads? I saw one article from a guys using those in a 1911 who said if he were to shoot it regularly he would probably switch from his 18lb spring to a 22 lb spring.
those calculators do not do a good job of actual burn rate estimation. it depends on the powder being used case internal volume seating depth primer etc. only real way to tell is using a pressure test barrel.